Cu(II) disrupts autophagy-mediated lysosomal degradation of oligomeric Aβ in microglia via mTOR-TFEB pathway
Xiaofang Tan, Huifeng Guan, Yang Yang, Shenying Luo, Lina Hou, Hongzhuan Chen, Juan Li
Topics & Concepts
TFEBAutophagyMicrogliaPI3K/AKT/mTOR pathwayCell biologyChemistryPhagocytosisBiologyMolecular biologySignal transductionBiochemistryImmunologyInflammationApoptosisAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments