Mesoporous hollow Fe<sub>3</sub>O<sub>4</sub> nanoparticles regulate the behavior of neuro-associated cells through induction of macrophage polarization in an alternating magnetic field
Weiru Guo, Xiaopei Wu, Wenying Wei, Youfa Wang, Honglian Dai
Abstract
, upregulate the expression of related genes and cytokines, and further promote the proliferation of neural stem cells and the subsequent migration of vascular endothelial cells. These effects were significantly enhanced after the application of an AMF. This work also showed that the internalization of particles is the starting point for polarization regulation.
Topics & Concepts
Materials scienceMacrophage polarizationPolarization (electrochemistry)Mesoporous materialNanoparticleMacrophageBiophysicsNanotechnologyBiologyChemistryBiochemistryPhysical chemistryIn vitroCatalysisGraphene and Nanomaterials ApplicationsNanoparticles: synthesis and applicationsNanoparticle-Based Drug Delivery