Antibiotic susceptibility profiling of Pseudomonas aeruginosa in nosocomial infection
Dipankar Das, Subhasish Kamilya, Vertika Rai, Sahana Ghosh, Hasina Perveen, Rupkatha Baidya, Shahanaz Khatun, Pratim Gupta, Yogesh Kisan Mali
Abstract
This paper aims to analyze the data regarding Pseudomonas aeruginosa causing nosocomial infection from different clinical samples in a tertiary hospital. The antimicrobial susceptibility pattern of Pseudomonas aeruginosa is observed to determine the sensitivity and resistance scenario of different antimicrobial agents in a hospital. We analyzed the data after gathering information on specimens (blood, pus, urine) and antibiotic susceptibility patterns. The study focused on various bacterial isolates that were obtained from a total of 40 samples. $32 \%$ of all infections were found to be caused by Pseudomonas aeruginosa, with 20% coming from Clostridium sp., 12% from Escherichia coli, 15% coming from Klebsiella sp. and Streptococcus pneumoniae, and 2% coming from Proteus sp. and Staphylococcus aureus. Data on antibiotic susceptibility tests revealed that Pseudomonas aeruginosa is sensitive to gentamycin and colistin but resistant to amoxicillin/ clavulanic acid, imipenem, levofloxacin, and cefoperazone/sulbactam. The study concludes that Pseudomonas aeruginosa is the primary cause of nosocomial infections; however, other bacteria including Clostridium sp., Escherichia coli, Klebsiella sp., Streptococcus pneumoniae, Proteus sp., and Staphylococcus aureus are also present. Pseudomonas aeruginosa infections can be treated with the antibiotic gentamycin and colistin.