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Caspase-11/4 and gasdermin D-mediated pyroptosis contributes to podocyte injury in mouse diabetic nephropathy

Qian Cheng, Jing Pan, Zhuanli Zhou, Fan Yin, Hongyan Xie, Panpan Chen, Jingyao Li, Peiqing Zheng, Li Zhou, Wei Zhang, Jun Liu, Limin Lü

2020Acta Pharmacologica Sinica183 citationsDOIOpen Access PDF

Topics & Concepts

PodocyteNephrinPodocinPyroptosisDiabetic nephropathySynaptopodinEndocrinologyInternal medicineMedicineProinflammatory cytokineCaspase 1InflammationInflammasomeKidneyProteinuriaInflammasome and immune disordersRenal Diseases and GlomerulopathiesBiomedical Research and Pathophysiology
Caspase-11/4 and gasdermin D-mediated pyroptosis contributes to podocyte injury in mouse diabetic nephropathy | Litcius