Facile <i>N</i>‐Formylation of Amines on Magnetic Fe<sub>3</sub>O<sub>4</sub>−CuO Nanocomposites
Kanchan Mishra, Hari Datta Khanal, Yong Rok Lee
Abstract
Abstract A facile, eco‐friendly, efficient, and recyclable heterogeneous catalyst is synthesized by immobilizing copper impregnated on mesoporous magnetic nanoparticles. The surface chemistry analysis of Fe 3 O 4 −CuO nanocomposites (NCs) by XRD and XPS demonstrates the synergistic effect between Fe 3 O 4 and CuO nanoparticles, providing mass‐transfer channels for the catalytic reaction. TEM images clearly indicate the impregnation of CuO onto mesoporous Fe 3 O 4 . This hydrothermally synthesized eco‐friendly and highly efficient Fe 3 O 4 −CuO NCs are applied as a magnetically retrievable heterogeneous catalyst for the N ‐formylation of wide range of aliphatic, aromatic, polyaromatic and heteroaromatic amines using formic acid as a formylating agent at room temperature. The catalytic activity of the NCs for N ‐formylation is attributable to the synergistic effect between Fe 3 O 4 and CuO nanoparticles. The N ‐formylated product is further employed for the synthesis of biologically active quinolone moieties.