Enantioselective Michael addition of aldehydes to maleimides catalysed by surface-adsorbed natural amino acids
Viktória Kozma, György Szőllősi
Abstract
Chiral hybrid materials obtained by adsorption of primary α-amino acids on the surface of inorganic oxides are economic, recyclable, highly enantioselective heterogeneous catalysts for the Michael addition of aldehydes to N -substituted maleimides.
Topics & Concepts
Enantioselective synthesisMichael reactionCatalysisChemistryAdsorptionOrganic chemistryAmino acidAddition reactionCombinatorial chemistryBiochemistrySurface Chemistry and CatalysisAnalytical Chemistry and ChromatographyAsymmetric Synthesis and Catalysis