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Evidence that coronavirus superspreading is fat-tailed

Felix Wong, James J. Collins

2020Proceedings of the National Academy of Sciences141 citationsDOIOpen Access PDF

Abstract

Superspreaders, infected individuals who result in an outsized number of secondary cases, are believed to underlie a significant fraction of total SARS-CoV-2 transmission. Here, we combine empirical observations of SARS-CoV and SARS-CoV-2 transmission and extreme value statistics to show that the distribution of secondary cases is consistent with being fat-tailed, implying that large superspreading events are extremal, yet probable, occurrences. We integrate these results with interaction-based network models of disease transmission and show that superspreading, when it is fat-tailed, leads to pronounced transmission by increasing dispersion. Our findings indicate that large superspreading events should be the targets of interventions that minimize tail exposure.

Topics & Concepts

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Transmission (telecommunications)Coronavirus2019-20 coronavirus outbreakFraction (chemistry)BiologyVirologyMedicineDiseaseChemistryInfectious disease (medical specialty)Internal medicineComputer scienceTelecommunicationsOrganic chemistryOutbreakCOVID-19 epidemiological studiesSARS-CoV-2 detection and testingSARS-CoV-2 and COVID-19 Research
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