Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation
Gui-Wei He, Lin Lin, Jeff DeMartino, Xuan Zheng, Nadzeya Staliarova, Talya L. Dayton, Harry Begthel, Willine J. van de Wetering, Eduard Bodewes, Jeroen S. van Zon, Sander J. Tans, Carmen López‐Iglesias, Peter J. Peters, Wei Wu, Daniel Kotlarz, Christoph Klein, Thanasis Margaritis, Frank C. P. Holstege, Hans Clevers
Topics & Concepts
OrganoidBiologyCell biologyDependency (UML)CellPaneth cellCryptIntestinal mucosaComputational biologyInternal medicineSmall intestineEndocrinologyBiochemistryComputer scienceMedicineSoftware engineeringIL-33, ST2, and ILC PathwaysCancer Cells and MetastasisImmune Cell Function and Interaction