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Blood cell-produced amyloid-β induces cerebral Alzheimer-type pathologies and behavioral deficits

Hao‐Lun Sun, Sihan Chen, Zhongyuan Yu, Yuan Cheng, Ding‐Yuan Tian, Dong‐Yu Fan, Chen-Yang He, Jun Wang, Pu‐Yang Sun, Yang Chen, Cheng‐Rong Tan, Junping Wang, Weihong Song, Huadong Zhou, Xiaowei Chen, Zhian Hu, Xian‐Le Bu, Yan‐Jiang Wang

2020Molecular Psychiatry59 citationsDOI

Topics & Concepts

NeuroinflammationPathogenesisTransplantationCerebral amyloid angiopathyMedicineMicrogliaGenetically modified mouseAlzheimer's diseaseBone marrowPathologyBlood–brain barrierNeuroscienceImmunologyTransgeneBiologyDiseaseEndocrinologyDementiaCentral nervous systemInternal medicineInflammationGeneBiochemistryAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsDementia and Cognitive Impairment Research
Blood cell-produced amyloid-β induces cerebral Alzheimer-type pathologies and behavioral deficits | Litcius