Chitosan targets PI3K/Akt/FoxO3a axis to up-regulate FAM172A and suppress MAPK/ERK pathway to exert anti-tumor effect in osteosarcoma
Zhaozhou Ren, Wan’an Xiao, Ming He, Lunhao Bai
Topics & Concepts
MAPK/ERK pathwayPI3K/AKT/mTOR pathwayProtein kinase BGene knockdownCell biologyCancer researchKinaseChemistryProtein kinase APhosphorylationSignal transductionOsteosarcomaBiologyMolecular biologyBiochemistryApoptosisAquaculture disease management and microbiotaMicroRNA in disease regulationInvertebrate Immune Response Mechanisms