From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease

Alastair Brown, Sophie J. Bradley, Fiona H. Marshall, Giles A. Brown, K.A. Bennett, Jason Brown, Julie E. Cansfield, David M. Cross, Chris de Graaf, Brian D. Hudson, Louis Dwomoh, João M. Dias, James C. Errey, Edward Hurrell, Jan Liptrot, Giulio Mattedi, Colin Molloy, Pradeep J. Nathan, Krzysztof Okrasa, Greg Osborne, Jayesh C. Patel, Mark Pickworth, N.J. Robertson, Shahram Shahabi, Christoffer Bundgaard, Keith G. Phillips, Lisa M. Broad, Anushka V. Goonawardena, Stephen R. Morairty, Michael Browning, Francesca Perini, Gerard R. Dawson, J.F.W. Deakin, R T Smith, Patrick M. Sexton, Julie Warneck, Mary Vinson, Tim Tasker, Benjamin G. Tehan, Barry Teobald, Arthur Christopoulos, Christopher J. Langmead, Ali Jazayeri, Roger Cooke, Prakash Rucktooa, Miles Congreve, Malcolm Weir, Andrew B. Tobin