Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?
G Dubourg, Jean‐Christophe Lagier, P. Brouqui, Jean‐Paul Casalta, Véronique Jacomo, Bernard La Scola, Jean‐Marc Rolain, Didier Raoult
Abstract
Among 275 patients with COVID-19, we found that median blood zinc level was significantly lower in patients with poor clinical outcome (N = 75) as compared to patients with good clinical outcome (N = 200) (840 μg/L versus 970 μg/L; p < 0.0001), suggesting that zinc supplementation could be useful for patients with severe COVID-19.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)ZincSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Medicine2019-20 coronavirus outbreakInternal medicineGastroenterologyVirologyChemistryOutbreakOrganic chemistryInfectious disease (medical specialty)DiseaseTrace Elements in HealthInfectious Encephalopathies and EncephalitisSARS-CoV-2 and COVID-19 Research