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The landscape of immune dysregulation in Crohn’s disease revealed through single-cell transcriptomic profiling in the ileum and colon

Lingjia Kong, Vladislav Pokatayev, Ariel Lefkovith, Grace T. Carter, Elizabeth A. Creasey, Chirag Krishna, Sathish Subramanian, Bharati Kochar, Orr Ashenberg, Helena Lau, Ashwin N. Ananthakrishnan, Daniel B. Graham, Jacques Deguine, Ramnik J. Xavier

2023Immunity26 citationsDOIOpen Access PDF

Topics & Concepts

IleumTranscriptomeStromal cellImmune systemDiseaseBiologyCrohn's diseaseImmune dysregulationColorectal cancerImmunologyCancer researchMedicineInternal medicineCancerGeneGeneticsEndocrinologyGene expressionInflammatory Bowel DiseaseMicroscopic ColitisGenetic factors in colorectal cancer
The landscape of immune dysregulation in Crohn’s disease revealed through single-cell transcriptomic profiling in the ileum and colon | Litcius