Malignancy-associated hemophagocytic lymphohistiocytosis in children: a 10-year experience of a single pediatric hematology center
Zhizhuo Huang, Yueping Jia, Ying‐xi Zuo, Jun Wu, Aidong Lu, Leping Zhang
Abstract
The M-HLH children with EBV infection are more likely to have prolonged APTT and more hemophagocytosis in BM. The M-HLH children had a poor prognosis, especially those with prolonged APTT.
Topics & Concepts
HemophagocytosisHemophagocytic lymphohistiocytosisMedicineMalignancySingle CenterInternal medicineGastroenterologyHematologyPediatricsLymphomaRetrospective cohort studyPartial thromboplastin timeBone marrowPancytopeniaDiseasePlateletAutoimmune and Inflammatory Disorders ResearchParvovirus B19 Infection StudiesImmune Cell Function and Interaction