Glabridin inhibits osteoarthritis development by protecting chondrocytes against oxidative stress, apoptosis and promoting mTOR mediated autophagy
Jihang Dai, Yaxin Zhang, Deng Chen, Duoyun Chen, Xiaolei Li, Jingcheng Wang, Yu Sun
Topics & Concepts
AutophagyOxidative stressPI3K/AKT/mTOR pathwayChemistryChondrocyteOsteoarthritisApoptosisPharmacologyIn vivoCartilageAggrecanCell biologyIn vitroBiochemistryMedicineBiologyAnatomyPathologyBiotechnologyAlternative medicineArticular cartilagePharmacological Effects of Natural CompoundsGinseng Biological Effects and ApplicationsAutophagy in Disease and Therapy