Bioinspired soft-hard combined system with mild photothermal therapeutic activity promotes diabetic bone defect healing via synergetic effects of immune activation and angiogenesis
Minhao Wu, Huifan Liu, Yufan Zhu, Ping Wu, Yun Chen, Zhouming Deng, Xiaobin Zhu, Lin Cai
Abstract
This work highlights the potential application of a photoactivated soft-hard combined system that provides long-term biophysical (mild photothermal stimulation) and biochemical (on-demand ion delivery) cues for accelerated healing of diabetic bone defects.
Topics & Concepts
Photothermal therapyAngiogenesisScaffoldExtracellular matrixChemistryRegeneration (biology)Bone healingRegenerative medicinePhotothermal effectBiomedical engineeringMaterials scienceCell biologyCancer researchNanotechnologyCellBiochemistryMedicineBiologyAnatomyMesenchymal stem cell researchNanoplatforms for cancer theranosticsPeriodontal Regeneration and Treatments