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Unveiling the inhibitory mechanism of peptidomimetic inhibitor against Aβ42 aggregation and protofibril disaggregation by molecular dynamics

Rajdeep Kaur, Rajneet Kaur Saini, Pritpal Singh, Bhupesh Goyal

2021Journal of Molecular Liquids10 citationsDOI

Topics & Concepts

PeptidomimeticChemistryMolecular dynamicsMonomerBiophysicsFibrilMolecular modelStereochemistryDocking (animal)Salt bridgeBiochemistryComputational chemistryPeptideOrganic chemistryPolymerBiologyNursingGeneMutantMedicineAlzheimer's disease research and treatmentsComputational Drug Discovery MethodsProtein Structure and Dynamics
Unveiling the inhibitory mechanism of peptidomimetic inhibitor against Aβ42 aggregation and protofibril disaggregation by molecular dynamics | Litcius