METTL1/WDR4-mediated tRNA m7G modification and mRNA translation control promote oncogenesis and doxorubicin resistance
Zhaoyu Wang, Peng Yu, Yutong Zou, Jieyi Ma, Hui Han, Wei Wei, Chunlong Yang, Siyi Zheng, Siyao Guo, Juan Wang, Lianlian Liu, Shuibin Lin
Topics & Concepts
OsteosarcomaBiologyGene knockdownCancer researchCarcinogenesisTranslation (biology)Messenger RNAMethyltransferaseTransfer RNATumor progressionMethylationRNACell biologyCancerGeneticsGeneRNA modifications and cancerCancer-related gene regulationCancer-related molecular mechanisms research