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Guillain-Barré syndrome associated with COVID-19 infection.

Hussein K. Manji, Upendo George, Namala Mkopi, Karim Manji

2020PubMed23 citationsDOIOpen Access PDF

Abstract

We are reporting a case of Acute Post-Infectious Flaccid paralysis also commonly known as Guillain-Barré Syndrome (GBS) in a patient with confirmed COVID-19 infection. GBS often occurs following an infectious trigger which induces autoimmune reaction causing damage to peripheral nerves. So far, only 8 cases have been described in association with COVID-19. This is the first to be described in Tanzania in an African Child, and probably the first in the continent. This report is presented for clinicians to be aware and for the medical fraternity to look into this unusual presentation which may shed some more light on possible pathways of the pathogenesis and clinical manifestations. We recommend that the presentation of GBS with acute respiratory distress should warrant extra precaution and a testing for COVID-19 especially when the symptoms of COVID-19 are protean.

Topics & Concepts

MedicineGuillain-Barre syndromeCoronavirus disease 2019 (COVID-19)Presentation (obstetrics)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Zika virusPediatricsAcute respiratory distressImmunologyWeaknessIntensive care medicineVirusPathologyInfectious disease (medical specialty)LungInternal medicineSurgeryDiseasePeripheral Neuropathies and DisordersLong-Term Effects of COVID-19Retinal and Optic Conditions
Guillain-Barré syndrome associated with COVID-19 infection. | Litcius