Structure, biochemistry, and gene expression patterns of the proline biosynthetic enzyme pyrroline-5-carboxylate reductase (PYCR), an emerging cancer therapy target
Alexandra Bogner, Kyle M. Stiers, John J. Tanner
Topics & Concepts
Proline dehydrogenaseBiologyProlineBiochemistryReductaseDownregulation and upregulationEnzymeGeneAmino acidCancer, Hypoxia, and MetabolismRNA modifications and cancerEnzyme Structure and Function