A novel network pharmacology approach for leukaemia differentiation therapy using Mogrify®
Lin Ming Lee, Eleni Christodoulou, Pavithra Shyamsunder, Bei Jun Chen, Kian Leong Lee, Tsz Kan Fung, Chi Wai Eric So, Gee Chuan Wong, Enrico Petretto, Owen J. L. Rackham, S. Tiong Ong
Topics & Concepts
IRF1BiologyTranscription factorMyeloidCellular differentiationCancer researchDifferentiation therapyComputational biologyAcute promyelocytic leukemiaCell cultureGeneticsGeneRetinoic acidRetinoids in leukemia and cellular processesProtein Degradation and InhibitorsAcute Myeloid Leukemia Research