Precision probiotic development based on gut microbial biomarkers: from mechanistic insights to clinical translation

Abstract

studies to assess microbial colonization dynamics and metabolic impacts, and advanced computational approaches combining machine learning algorithms with multi-omics data analysis. Such an integrated approach facilitates the identification of gut microbial biomarkers and the development of precision probiotics, while requiring further refinement of algorithm-driven outcome prediction models and establishment of cross-population validation protocols, thereby accelerating the translation of gut microbiome research into personalized therapeutic strategies and advancing the frontier of precision medicine in gastrointestinal health.

Topics & Concepts