Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry
Jinwoo Lee, Alex J.B. Kreutzberger, Laura Odongo, Elizabeth A. Nelson, David A. Nyenhuis, Volker Kiessling, Binyong Liang, David S. Cafiso, Judith M. White, Lukas K. Tamm
Topics & Concepts
EndosomeLipid bilayer fusionNPC1Ebola virusGlycoproteinViral entryCell biologyCell fusionMembrane glycoproteinsViral membraneTransmembrane proteinCell membraneCholesterolTransmembrane domainChemistryFusion proteinVirologyVirusBiologyViral envelopeCellMembraneBiochemistryViral replicationReceptorRecombinant DNAGeneViral Infections and Outbreaks Researchinterferon and immune responsesMosquito-borne diseases and control