Genistein protects against acetaminophen-induced liver toxicity through augmentation of SIRT1 with induction of Nrf2 signalling
Linpei Wang, Anquan Li, Yinhao Liu, Shiyang Zhan, Lei Zhong, Youqin Du, Dongyao Xu, Wei Wang, Weifeng Huang
Topics & Concepts
GenisteinAcetaminophenDownregulation and upregulationPharmacologyLiver injuryGlutathioneGene knockdownChemistryToxicityMalondialdehydeEndocrinologyAntioxidantBiochemistryBiologyEnzymeApoptosisOrganic chemistryGeneGenomics, phytochemicals, and oxidative stressDrug-Induced Hepatotoxicity and ProtectionSirtuins and Resveratrol in Medicine