Facile synthesis of silver nanoparticles using leaf extract of Hyptis suaveolens (L.) Poit for environmental and biomedical applications
Agbaje Lateef, Suliat M. Oladejo, Paul O. Akinola, Daniel Ayandiran Aina, Lorika S. Beukes, Bolaji I. Folarin, E.B. Gueguim Kana
Abstract
Abstract Aqueous leaf extract of Hyptis suaveolens was investigated to synthesize silver nanoparticles (Hs-AgNPs). Biomolecules such as phenolics, proteins, carbohydrates and esters facilitated bioformation of Hs-AgNPs with ƛmax at 420 nm. The nearly spherical Hs-AgNPs were polydispersed and sized 29.19-52.27 nm with yield of 85.8 %. Hs-AgNPs showed potent inhibition of 75.22-100 % against multidrug resistant bacteria, and fungal growth inhibition of 73.33-100 %. Hs-AgNPs scavenged DPPH and H 2 O 2 by 77.75-83.19, and 54.21-70.11 % respectively. It also effectively inhibited coagulation of blood. The study established the nanobiotechnological importance of H. suaveolens , with bioformation of AgNPs that have potent activities for environmental and biomedical applications.