Microglia sense neuronal activity via GABA in the early postnatal hippocampus
Francesca Logiacco, Pengfei Xia, Svilen Veselinov Georgiev, Celeste Franconi, Yi‐Jen Chang, Bilge Ugursu, Anje Sporbert, Ralf Kühn, Helmut Kettenmann, Marcus Semtner
Abstract
receptors in microglia. This neuron, astrocyte, and microglia communication pathway might modulate microglial activity in developing neuronal networks.
Topics & Concepts
MicrogliaNeuroscienceGlutamate receptorPremovement neuronal activityStimulationAstrocyteBiologyHippocampusGABAB receptorReceptorNeurogliaCentral nervous systemChemistryGABAA receptorInflammationBiochemistryImmunologyNeuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms