Litcius/Paper detail

Genotoxicity evaluation of a valsartan-related complex N-nitroso-impurity

Susanne Glowienke, Ulrich Onken, Azeddine Elhajouji, Sasikumar Muthusamy, Ramachandra Sangana, Hans‐Joerg Martus, Timothy Bedman, Andreas Hartmann

2022Regulatory Toxicology and Pharmacology28 citationsDOI

Topics & Concepts

Ames testGenotoxicityChemistryNitrosationCarcinogenPharmacologyValsartanDrugNitroso CompoundsBiochemistryToxicityOrganic chemistryGeneticsBiologyMedicineInternal medicineBacteriaSalmonellaBlood pressureCarcinogens and Genotoxicity AssessmentWater Treatment and DisinfectionPolyamine Metabolism and Applications