TIPE-mediated up-regulation of MMP-9 promotes colorectal cancer invasion and metastasis through MKK-3/p38/NF-κB pro-oncogenic signaling pathway
Huiyu Chen, Yuhan Ye, Yan Yang, Mengya Zhong, Lei Gu, Zhaopu Han, Jinhua Qiu, Zhongchen Liu, Xingfeng Qiu, Guohong Zhuang
Topics & Concepts
Cancer researchMatrix metalloproteinaseMetastasisColorectal cancerSignal transductionNF-κBp38 mitogen-activated protein kinasesMedicineCancerBiologyMAPK/ERK pathwayCell biologyInternal medicineCancer Mechanisms and TherapySignaling Pathways in DiseaseCancer Research and Treatments