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Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids

Galina Popova, Sarah S. Soliman, Chang N. Kim, Matthew G. Keefe, Kelsey M. Hennick, Samhita Jain, Tao Li, Darío Tejera, David Shin, Bryant B. Chhun, Christopher S. McGinnis, Matthew L Speir, Zev J. Gartner, Shalin B. Mehta, Maximilian Haeussler, Keith B. Hengen, Richard M. Ransohoff, Xianhua Piao, Tomasz J. Nowakowski

2021Cell stem cell227 citationsDOIOpen Access PDF

Topics & Concepts

MicrogliaBiologyOrganoidInduced pluripotent stem cellStem cellNeuroscienceNeural stem cellCell typeCell biologyPhenotypeCellular differentiationCellEmbryonic stem cellGeneImmunologyGeneticsInflammationNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancerBarrier Structure and Function Studies
Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids | Litcius