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Rapid-acting and long-lasting antidepressant-like action of (R)-ketamine in Nrf2 knock-out mice: a role of TrkB signaling

Youge Qu, Jiajing Shan, Siming Wang, Lijia Chang, Yaoyu Pu, Xingming Wang, Yunfei Tan, Masayuki Yamamoto, Kenji Hashimoto

2020European Archives of Psychiatry and Clinical Neuroscience41 citationsDOI

Topics & Concepts

KetamineBehavioural despair testTail suspension testTropomyosin receptor kinase BAntidepressantPharmacologyAntagonistNMDA receptorChemistryEndocrinologyInternal medicineMedicineBiologyReceptorNeuroscienceNeurotrophic factorsHippocampusTryptophan and brain disordersStress Responses and CortisolTreatment of Major Depression
Rapid-acting and long-lasting antidepressant-like action of (R)-ketamine in Nrf2 knock-out mice: a role of TrkB signaling | Litcius