IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors
Lauren Giuffrida, Kevin Sek, Melissa A. Henderson, Imran G. House, Junyun Lai, Amanda X. Y. Chen, Kirsten L. Todd, Emma V. Petley, Sherly Mardiana, Izabela Todorovski, Emily Gruber, Madison J. Kelly, Benjamin Solomon, Stephin J. Vervoort, Ricky W. Johnstone, Ian A. Parish, Paul J. Neeson, Lev M. Kats, Phillip K. Darcy, Paul A. Beavis
Topics & Concepts
Chimeric antigen receptorCancer researchT cellCD28ImmunologyBlockadeCD8ImmunotherapyMedicineCytotoxic T cellImmune systemBiologyReceptorInternal medicineIn vitroBiochemistryCAR-T cell therapy researchImmune Cell Function and InteractionImmunotherapy and Immune Responses