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A multimodal submillimeter MRI atlas of the human cerebellum

Wenjiao Lyu, Ye Wu, Khoi Minh Huynh, Sahar Ahmad, Pew‐Thian Yap

2024Scientific Reports17 citationsDOIOpen Access PDF

Abstract

The human cerebellum is engaged in a broad array of tasks related to motor coordination, cognition, language, attention, memory, and emotional regulation. A detailed cerebellar atlas can facilitate the investigation of the structural and functional organization of the cerebellum. However, existing cerebellar atlases are typically limited to a single imaging modality with insufficient characterization of tissue properties. Here, we introduce a multifaceted cerebellar atlas based on high-resolution multimodal MRI, facilitating the understanding of the neurodevelopment and neurodegeneration of the cerebellum based on cortical morphology, tissue microstructure, and intra-cerebellar and cerebello-cerebral connectivity.

Topics & Concepts

CerebellumNeuroscienceAtlas (anatomy)CognitionNeuroimagingHuman brainComputer scienceAnatomyPsychologyBiologyAdvanced Neuroimaging Techniques and ApplicationsFetal and Pediatric Neurological DisordersAdvanced MRI Techniques and Applications
A multimodal submillimeter MRI atlas of the human cerebellum | Litcius