Shikimate Metabolic Pathway Engineering in <i>Corynebacterium glutamicum</i>
Eunhwi Park, Hyejin Kim, Seung-Yeul Seo, Hanna Lee, Si-Sun Choi, Sang Joung Lee, Eung‐Soo Kim
Abstract
strain grown in an optimized medium produced approximately 37.3 g/l of shikimate in 7-L fed-batch fermentation. Overall, rational cell factory design and culture process optimization for the microbial-based production of shikimate will play a key role in complementing traditional plant-derived shikimate production processes.
Topics & Concepts
Corynebacterium glutamicumShikimate pathwayShikimic acidBiochemistryMetabolic engineeringBiologyAromatic amino acidsAmino acidGeneMicrobial Metabolic Engineering and BioproductionViral Infectious Diseases and Gene Expression in InsectsBiofuel production and bioconversion