Litcius/Paper detail

Functional and protective hole hopping in metalloenzymes

Harry B. Gray, Jay R. Winkler

2021Chemical Science75 citationsDOIOpen Access PDF

Abstract

. In many cases these chains may serve a protective role in metalloenzymes by deactivating high-potential reactive intermediates formed in uncoupled catalytic turnover.

Topics & Concepts

ChemistryDensity functional theoryCombinatorial chemistryNanotechnologyMaterials scienceComputational chemistryPorphyrin Metabolism and DisordersPhotosynthetic Processes and MechanismsEnzyme Structure and Function