A Longitudinal Study of Adult Patients with<i>Staphylococcus aureus</i>Bacteremia over 11 Years in Korea
Seong Ho Choi, Jeong‐Soo Lee, Jiwon Jung, Eun Sil Kim, M.J. Kim, Yong Pil Chong, Sung‐Han Kim, Sang‐Oh Lee, Sang‐Ho Choi, Jun Hee Woo, Yang Soo Kim
Abstract
BACKGROUND: bacteremia (SAB) and the corresponding clinical changes over the last decade in South Korea are rarely investigated. METHODS: ) typing. Trends in changes were identified by linear regression analysis. RESULTS: -t008-MRSA (USA300) was found in 28.6%. Central venous catheter (CVC)-related SAB (-2.440%/yr) and persistent SAB (-1.016%/yr) decreased, but mortality and recurrence rates were unchanged. CONCLUSION: Over the last decade, the hospital clones ST5 and ST239 have been replaced by community genotype ST72. This was associated with decreased CVC-related and persistent SAB. Increased USA300 was observed in community and hospital settings. Further research is required to identify the reasons for the ST72 epidemic and predict the impending epidemic of ST8 strains, including USA300.