Central and peripheral innate and adaptive immunity in Parkinson’s disease
Ashley S. Harms, Yating Yang, Malú G. Tansey
Abstract
Parkinson's disease (PD) is a multisystem disorder with characteristics of a chronic inflammatory disease. To develop effective immunomodulatory interventions to combat PD, we need to think innovatively about the implications of orchestrated central and peripheral innate and adaptive immune responses that occur as the disease begins and progresses.
Topics & Concepts
Innate immune systemDiseaseParkinson's diseasePeripheralAcquired immune systemImmunityImmunologyMedicineImmune systemInflammationNeuroscienceBiologyPathologyInternal medicineParkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration MechanismsNuclear Receptors and Signaling