Design, synthesis, and biological evaluation of novel dual inhibitors targeting lysine specific demethylase 1 (LSD1) and histone deacetylases (HDAC) for treatment of gastric cancer
Ying‐Chao Duan, Linfeng Jin, Hongmei Ren, Shaojie Zhang, Yue-Jiao Liu, Yongtao Xu, Zihao He, Yu Song, Hang Yuan, Shuhui Chen, Yuanyuan Guan
Topics & Concepts
ChemistryADMECancer cellCancerHistone deacetylaseDemethylaseBiochemistryCell growthPharmacologyIn vitroCancer researchHistoneBiologyGeneticsGeneHistone Deacetylase Inhibitors ResearchEpigenetics and DNA MethylationProtein Degradation and Inhibitors