Biased and allosteric modulation of bone cell-expressing G protein-coupled receptors as a novel approach to osteoporosis therapy
Alexander Kalinkovich, Gregory Livshits
Topics & Concepts
Bone resorptionBone remodelingOsteoporosisReceptorOsteoprotegerinWnt signaling pathwayChemistryG protein-coupled receptorSignal transductionBone cellCell biologyPharmacologyEndocrinologyInternal medicineMedicineBiologyActivator (genetics)Bone health and treatmentsBone Metabolism and DiseasesEstrogen and related hormone effects