MALDI-TOF MS Is an Effective Technique To Classify Specific Microbiota
Liangqiang Chen, Wenjing Gao, Xue Tan, Ying Han, Jiao Fu, Bin Feng, Jinghang Xie, Bin Li, Huilin Zhao, Huabin Tu, Shaoning Yu, Li Wang
Abstract
MALDI-TOF MS can be used to classify specific model microbiota. The actual MS spectrum of the model microbiota was not a simple superposition of every single bacterium in a certain proportion but had a specific spectral fingerprint. The specificity of this fingerprint can enhance the accuracy of microbiota classification.
Topics & Concepts
Matrix-assisted laser desorption/ionizationHierarchical clusteringComputational biologyMass spectrometryBacterial taxonomyIdentification (biology)BiologyMicrobiologyBacteriaCluster analysisChemistryChromatographyArtificial intelligenceGenetics16S ribosomal RNAComputer scienceEcologyAdsorptionOrganic chemistryDesorptionBacterial Identification and Susceptibility TestingUrinary Tract Infections ManagementGut microbiota and health