How long-term air pollution and its metal constituents affect type 2 diabetes mellitus prevalence? Results from Wuhan Chronic Disease Cohort
Meijin Chen, Qiujun Qin, Feifei Liu, Yixuan Wang, Chuangxin Wu, Yaqiong Yan, Hao Xiang
Abstract
BACKGROUND: Epidemiological evidence linking type 2 diabetes mellitus (T2DM) with air pollution is discrepant and most are restricted to the influences of air-pollutant mass concentration. This study aims to explore the effects of long-term exposure to air pollution and its metal constituents on T2DM prevalence in China. METHODS: metal constituents prior to the baseline investigation. RESULTS: were significant risk factors to T2DM with odds ratios of 1.350 (95%CI: 1.089, 1.673) and 1.389 (95%CI: 1.164, 1.658) for per IQR increase, respectively. Stratification analyses indicated that males and those aged ≥45 years were more susceptive to long-term air pollution. CONCLUSIONS: . Further research to validate these results and to clarify the underlying mechanisms is warranted.