Distinct Persistence Fate of Mycobacterium tuberculosis in Various Types of Cells
Xi Chen, Xiaojian Cao, Yingying Lei, Aikebaier Reheman, Wei Zhou, Bing Yang, Weipan Zhang, Weize Xu, Shuang Dong, Rohit Tyagi, Zhen F. Fu, Gang Cao
Abstract
As an intracellular pathogen, Mycobacterium tuberculosis could avoid host cell immune clearance using multiple strategies for its long-term survival. Understanding these processes could facilitate the development of new approaches to restrict intracellular M. tuberculosis survival.
Topics & Concepts
Mycobacterium tuberculosisPhagosomeBiologyTuberculosisIntracellular parasiteIntracellularAutophagyCell cultureCell biologyA549 cellMicrobiologyGeneticsMedicineApoptosisPathologyTuberculosis Research and EpidemiologyAutophagy in Disease and TherapyHIV Research and Treatment