Data highlighting phenotypic diversity of urine-associated Escherichia coli isolates
Allison R. Eberly, Connor J. Beebout, Ching Man Carmen Tong, Gerald T. Van Horn, Hamilton D. Green, Madison J. Fitzgerald, Shuvro De, Emily K. Apple, Alexandra C. Schrimpe‐Rutledge, Simona G. Codreanu, Stacy D. Sherrod, John A. McLean, Douglass B. Clayton, Charles W. Stratton, Jonathan E. Schmitz, Maria Hadjifrangiskou
Abstract
This article provides a reusable dataset describing detailed phenotypic and associated clinical parameters in n=303 clinical isolates of urinary Escherichia coli collected at Vanderbilt University Medical Center. De-identified clinical data collected with each isolate are detailed here and correlated to biofilm abundance and metabolomics data. Biofilm-abundance data were collected for each isolate under different in vitro conditions along with datasets quantifying biofilm abundance of each isolate under different conditions. Metabolomics data were collected from a subset of bacterial strains isolated from uncomplicated cases of cystitis or cases with no apparent symptoms accompanying colonization. For more insight, please see “Defining a Molecular Signature for Uropathogenic versus Urocolonizing Escherichia coli: The Status of the Field and New Clinical Opportunities” [1].