CRISPR-empowered electrochemical biosensor for target amplification-free and sensitive detection of miRNA
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang, Kaixiang Zhang
Topics & Concepts
CRISPRTrans-activating crRNAConcatemerChemistryBiosensorDetection limitDNACas9DeoxyribozymeComputational biologyCombinatorial chemistryNanotechnologyGeneBiologyBiochemistryChromatographyGenomeMaterials scienceCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery