Sensitive and selective “signal-off” electrochemiluminescence sensing of prostate-specific antigen based on an aptamer and molecularly imprinted polymer
Yuanyuan Wang, Xianwen Kan
Abstract
, respectively. Compared with individual aptamer sensors, the dual-recognition sensor showed higher specific recognition ability for the determination of PSA. Meanwhile, the good stability, reproducibility, and regenerability endowed the dual recognition sensor with favorable application value in early clinical diagnosis.
Topics & Concepts
AptamerMolecularly imprinted polymerElectrochemiluminescenceDetection limitMolecular recognitionChemistryProstate-specific antigenColloidal goldBiomarkerProstate cancerCombinatorial chemistryNanotechnologyChromatographyMaterials scienceNanoparticleSelectivityCancerMolecular biologyMoleculeBiochemistryMedicineInternal medicineBiologyCatalysisOrganic chemistryAdvanced biosensing and bioanalysis techniquesAnalytical chemistry methods developmentIon-surface interactions and analysis