Litcius/Paper detail

Discovery of NLRP3 inhibitors using machine learning: Identification of a hit compound to treat NLRP3 activation-driven diseases

Cheng Shi, Xiangyu Zhang, Xiaowei Chi, Yi Zhou, Weiping Lyu, Tongfei Gao, Jiaxu Zhou, Yanming Chen, Chuxiao Yi, Xiaojiao Sun, Liangren Zhang, Zhenming Liu, Zhenming Liu

2023European Journal of Medicinal Chemistry13 citationsDOIOpen Access PDF

Topics & Concepts

In vivoChemistryDrug discoveryLead compoundPharmacologyCytotoxicitySmall moleculeIn vitroComputational biologyBiochemistryMedicineBiologyBiotechnologyInflammasome and immune disordersCholesterol and Lipid MetabolismSphingolipid Metabolism and Signaling
Discovery of NLRP3 inhibitors using machine learning: Identification of a hit compound to treat NLRP3 activation-driven diseases | Litcius