Litcius/Paper detail

Microenvironmental regulation of solid tumour resistance to CAR T cell therapy

Zachary L Lamplugh, Nils Wellhausen, Carl H. June, Yi Fan

2025Nature reviews. Immunology19 citationsDOI

Topics & Concepts

Chimeric antigen receptorImmunotherapyT cellCancer researchTumor microenvironmentReprogrammingImmune systemCell therapyCellCancer immunotherapySuppressorAntigenCAR T-cell therapyBiologyImmunologyCytotoxic T cellMedicineChemistryImmune checkpointPD-L1CAR-T cell therapy researchImmunotherapy and Immune ResponsesImmune Cell Function and Interaction