Novel complementary coloprotective effects of metformin and MCC950 by modulating HSP90/NLRP3 interaction and inducing autophagy in rats
Sameh Saber, Eman M. Abd El-Kader
Topics & Concepts
MetforminAutophagyInflammasomeInflammationPyroptosisPharmacologyMyeloperoxidaseTLR4HMGB1MedicineTumor necrosis factor alphaAMPKApoptosisChemistryImmunologyEndocrinologyProtein kinase AKinaseDiabetes mellitusBiochemistryInflammasome and immune disordersAutophagy in Disease and TherapyHeme Oxygenase-1 and Carbon Monoxide