Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan
Raúl Castro-Portuguez, George L. Sutphin
Topics & Concepts
NAD+ kinaseMitochondrionNicotinamide adenine dinucleotideBiologyOxidative stressBiochemistryMitophagyCell biologyOxidative phosphorylationKynurenine pathwayMetabolic pathwayLongevityKynurenineMetabolismAutophagyEnzymeTryptophanGeneticsAmino acidApoptosisTryptophan and brain disordersSirtuins and Resveratrol in MedicineCircadian rhythm and melatonin