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Visible Light-Induced Cascade Cyclization of 3-Aminoindazoles, Ynals, and Chalcogens: Access to Chalcogen-Containing Pyrimido[1,2-<i>b</i>]-indazoles

Jinlei Zhou, Wen Li, Huitao Zheng, Yongyan Pei, Xiang Liu, Hua Cao

2021Organic Letters60 citationsDOI

Abstract

A direct cascade cyclization of 3-aminoindazoles, ynals, and accessible chalcogens facilitated by visible light has been developed. A series of fluoroactive selenium/tellurium-substituted pyrimido[1,2-b]-indazoles were easily accessed in moderate to good yields with a broad scope. Furthermore, we surveyed the spectral properties of selenide pyrimido[1,2-b]-indazoles prepared by this method.

Topics & Concepts

ChalcogenChemistrySelenideTelluriumCascadeSeleniumThio-StereochemistryCrystallographyOrganic chemistryChromatographySulfur-Based Synthesis TechniquesOrganoselenium and organotellurium chemistryRadical Photochemical Reactions
Visible Light-Induced Cascade Cyclization of 3-Aminoindazoles, Ynals, and Chalcogens: Access to Chalcogen-Containing Pyrimido[1,2-<i>b</i>]-indazoles | Litcius