Bacterial Extracellular Vesicles and Antimicrobial Peptides: A Synergistic Approach to Overcome Antimicrobial Resistance
Corina Ciobănaşu
Abstract
Antimicrobial resistance is already a major global health threat, contributing to nearly 5 million deaths annually. The rise of multidrug-resistant pathogens has made many infections increasingly difficult to treat. This growing threat has driven the search for alternative therapeutic approaches. Among the most promising candidates are bacterial extracellular vesicles (BEVs) and antimicrobial peptides (AMPs), which offer unique mechanisms of action, potential synergistic effects, and the ability to bypass conventional resistance pathways. This review summarizes the current research on synergistic effects of BEVs and AMPs to overcome antimicrobial resistance.
Topics & Concepts
AntimicrobialAntimicrobial peptidesAntibiotic resistanceExtracellular vesiclesMultiple drug resistanceMicrobiologyDrug resistanceAnti-Infective AgentsBiologyAntibioticsBiotechnologyCell biologyBacterial Infections and VaccinesAntimicrobial Peptides and ActivitiesPneumonia and Respiratory Infections